FLEXIBLE HEALING

Injured tendons and ligaments typically take between one to two years to completely heal after surgery. During the first 6-12 weeks, the body must eliminate damaged and dead tissue, which greatly reduces the strength of the surgical repair. During return to activity, these repairs often become stretched or fail entirely. It is common to reinforce these repairs; these reinforcements come in three primary forms:

Autograft :: tissue harvested from another part of your own body
Allograft, Xenograft :: tissue acquired from deceased donors or other animal species
Synthetic :: scientifically designed materials that substitute for the body’s own tissues

Your body’s natural way of moving requires STRONG and ELASTIC tendons and ligaments. After implantation, graft materials weaken rapidly due to immune reaction, and have been shown to lose 50-90% of their strength within the first six weeks.1,2 These reinforcements are often much stiffer than native tendons and ligaments, altering mechanics at the healing site. These stiffness changes can have profound negative effects on long-term motion, joint surfaces, and tissue healing.
Artelon’s proven innovations in Dynamic Matrix technology protects the repair AND natural motion throughout the entire tissue healing process.

1. Weiler, A. et al, Biomechanical Properties and vascularity of an anterior cruciate ligament graft can be predicted by contrast-enhanced magnetic resonance imaging. A two year study of sheep. Am JSports Med 2001, 26(6): 751-761.
2. Steinmann et al. Rotator cuff repair using an acellular dermal matrix graft: an in vivo study in a canine model. Arthroscopy, 2006 Jul;22(7):700-9.
DYNAMIC DESIGN
Artelon’s Dynamic Matrix products were designed with STRENGTH and ELASTICITY to enhance both the Biology and the Mechanics of connective tissue reconstruction.
STRENGTH
  • Immediate protection and support of the repair
  • Maintains strength throughout the entire healing process, unlike grafts
  • Elastic material strength does not over-constrain or stress shield
ELASTICITY
  • Moves like the body’s natural tissues
  • Resists stretching out over time, or creep
  • Creates resilient environment for tissue healing
More than 40,000 patients have experienced Flexible Healing worldwide; and more than 20 individual published studies prove Artelon is the advanced solution for connective tissue reconstruction.
DYNAMIC ACTION
These critical properties drive industry leading Bio + Mechanical modes of action that optimize tendon and ligament repair:

RESTORE
Restores Stability and Natural Motion

Doubles the reconstruction strength without altering stiffness1

Stretches like natural tendon and ligament

Permits natural motion

RESIST
Resists Degradation of the Mechanical and Elastic Properties

Impervious to necrotic breakdown during the early phase of healing

Maintains 90% of its strength and elasticity through the first year of healing2

Less inflammatory than common biocompatible materials (titanium, polystyrene, and resorbable suture)3

RE-ESTABLISH
Regenerates Native Connective Tissue

Artelon’s Dynamic Matrix:

Promotes load sharing with native tissue which induces biological signaling responsible for tissue regeneration4

Integrates and is replaced by regenerated tissue over 4-5 years22

1. Gersoff WK et al. Evaluation of a Novel Degradable Synthetic Biomaterial Patch for Augmentation of Tendon Healing in a Large Animal Model. J Knee Surg. 2018 Apr 27.
2. Data on File
3. Liljensten et al. Studies of polyurethane urea bands for ACL reconstruction. J. Biomater. Sci: Materials in Medicine 13 (2002) 351-359
4. Galloway MT1, Lalley AL, Shearn JT. The role of mechanical loading in tendon development, maintenance, injury, and repair. J Bone Joint Surg Am. 2013 Sep 4;95(17):1620-8.
DYNAMIC BENEFITS
ARTELON DYNAMIC MATRIXTissue GraftsSuture/Tape-Type Augmentation
Enhance Strength
Yes

Temporarily
Maintain Natural Tissue Stiffness
Yes

Too Stiff

Too Stiff
Tissue Regeneration
Elasticity driven cellular activation, proliferation, and maturation; Optimized cellular porosity

Cellular scaffold

Permanent implant, non-regenerative
Consistent Fixation
Yes

Variability due to donor tissue

Yes
Reconstruction Tensioning
Broad elastic profile promotes reproducible surgical tensioning

None

Inelastic material acts as a check rein. Sets boundaries of motion, but does not support tissue elasticity.
Risk of Disease Transmission
No

Yes

No
Shelf Life
5 Years

Typically < 2yrs

5 years
PRODUCTS
Artelon’s Dynamic Matrix is a proprietary bio-textile, knitted from fibers made from a co-polymer blend of polycaprolactone and polyurethane urea. The copolymer establishes the steady 4-6 year dissolution rate, while the knit defines strength, elasticity, and optimized regenerative ingrowth porosity.
These Dynamic Matrices are in two clinical forms:
FLEXBANDTM

The FlexBand strip is 1.2cm thick and comes strips of various widths and lengths and is commonly chosen to enhance the reconstruction of ligaments and tendons through the extremities. Examples include:

  • Achilles Tendon
  • Lateral Ankle
  • Plantar Plate
  • Spring Ligament
  • Anterior Tibial Tendon
  • Posterior Tibial Tendon
  • ACL
  • MCL

Available Sizes

  • 0.3cm x 8cm, 0.3cm x 16 cm
  • 0.5cm x 8cm, 0.5cm x 16cm
  • 0.7cm x 8cm, 0.7cm x 16cm, 0.7 x 32cm
FLEXPATCHTM

The FlexPatch is roughly half the thickness of the FlexBand and is commonly chosen to enhance reconstruction of larger tendons and ligaments such as:

  • Knee Extensor Mechanism
  • Superior Capsule Reconstruction
  • Hip Abductors/Posterior Capsule

Available Sizes

  • 3cm x 4cm
  • 4cm x 6cm
  • 6cm x 9cm
ABOUT US

The original vision for Artelon was cast by world renown orthopedic surgeon Lars Peterson, MD. His experience clinically investigating multiple failed synthetic tendon and ligament devices highlighted key design features necessary for a synthetic material to demonstrate real world success in connective tissue reconstruction. Working with an elite team of chemists, textile engineers Dr. Peterson’s vision came to fruition in the form of Artelon’s Dynamic Matrix. Since it’s inception, this technology has delivered on it’s promise of enhanced biological and mechanical soft tissue reconstruction with over 40,000 implantations worldwide.

Today Artelon is US owned and headquartered in Marietta, GA, and is committed to continuing innovation to re-establish joint stability and kinematics through novel soft tissue reconstructive products and procedures.

CONTACT US

Artelon
2252 Northwest Pkwy SE
Suite G
Marietta, GA 30067

800.610.3446
customerservice@artelon.com

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